(P1-93) Apathy Syndrome

SSRI-induced apathy syndrome: a clinical review.

The authors review the literature pertaining to selective serotonin reuptake inhibitor (SSRI)-induced apathy syndrome. A literature search of Medline and International Pharmaceutical Abstracts from 1970 to the present was performed for relevant articles. Twelve relevant case reports and one open-label treatment trial were identified. An amotivational, or apathy, syndrome has been reported in a ...

Apathy : An Ignored Neuropsychiatric Syndrome in South Africa

Apathy is a common feature of brain disorders, yet is often confused with depression and ignored by clinicians. This situation is problematic because apathy is associated with several adverse outcomes, including caregiver distress and decreased treatment adherence. This study investigated the prevalence of apathy and depression in 10 outpatients (7 women, 3 men, mean age = 63.7 years) at a Sout...

Apathy: a common psychiatric syndrome in the elderly.

Apathy, or a lack of motivation, has been increasingly recognized as a distinct psychiatric syndrome. Apathy is primarily a dysfunction of the frontal-subcortical circuit and is associated with various neuropsychiatric disorders including Alzheimer's disease. Apathy is associated with a number of adverse outcomes, including apparent cognitive impairment, decreased daily function, poor insight i...

Poststroke apathy.

Developing a new apathy measurement scale: Dimensional Apathy Scale.

Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including motor system disorders, that affects motivation to display goal directed functions. Levy and Dubois (2006) suggested three apathetic subtypes, Cognitive, Emotional-affective and Auto-activation, all with discrete neural correlates and functional impairments. The aim of this study was to create a new apathy m...